NewslettersIntestinal Cell News Enteropathogenic Bacteria Evade ROCK-Driven Epithelial Cell Extrusion By Noshin Noorjahan - October 22, 2025 0 60 The authors showed that the Escherichia coli ubiquitin ligase NleL is an inhibitor of intestinal epithelial cell extrusion, targeting caspase-4, ROCK1 and ROCK2 for proteasomal degradation. [Nature] Full Article