Synthetic Bottlebrush Block Copolymer Prevents Disease Onset in Duchenne Muscular Dystrophy

Data showed the remarkable potency of a synthetic poly(ethylene oxide)/poly(propylene oxide) side chain–based bottlebrush block copolymer, ~150,000 times more potent than linear polymers, to rapidly restore contractile function to Duchenne muscular dystrophy skeletal muscle fibers in vitro.