Shear Stress-Mediated Downregulation of Mir-423-5p in M2 Macrophage Exosomes Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells

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Scientists explored the regulatory mechanism of miR-423-5p in M2 macrophage exosomes on the osteogenic differentiation of bone marrow MSCs under a mechanical microenvironment, providing a theoretical basis for cell-free fracture repair therapy.
[International Immunopharmacology]
AbstractGraphical Abstract