MAPK Signaling and Angiopoietin-2 Contribute to Endothelial Permeability in Capillary Malformations

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Investigators have shown the involvement of the MAPK pathway and the pro-angiogenic molecule ANGPT2 in endothelial permeability, suggesting a potential target in GNAQ p.R183Q-driven capillary malformations.
[Proceedings of The National Academy of Sciences of The United States of America]
Abstract