Engineering CCR2/IFN-γ Overexpression in Enucleated Mesenchymal Stem Cells Enhances Therapy for Rheumatoid Arthritis

By
Emily Salmini
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Investigators generated enucleated human umbilical cord-derived MSCs overexpressing CCR2 and IFN-γ, which retained essential organelles and exhibited immune regulatory, paracrine, and homing capabilities.
[Communications Biology]
Abstract