Prostaglandin E-EP2/EP4 Signaling Induces the Tumor-Infiltrating Treg Phenotype for Tumor Growth

By
Emily Salmini
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Investigators showed that prostaglandin E2 (PGE2) produced in tumor microenvironment directly acts on its receptor EP2/EP4 on Tregs to induce the tumor-infiltrating Treg phenotype.
[Proceedings of the National Academy of Sciences of the United States of America]
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