Pathogenic Role of IFNγ from Activated CD4+ T Cells in Lupus Model Mice Induced by Topical Treatment with Toll-Like Receptor Agonist Imiquimod

Researchers explored the role of activated CD4⁺ T cells on the pathogenesis of lupus using systemic lupus erythematosus murine models induced by Toll like receptor 7 agonist imiquimod.