USP11 Promotes Colorectal Cancer Progression by Stabilizing EGFR and TRAF6: A Potential Therapeutic Target in EGFR- and TLR-Driven Tumorigenesis

Researchers investigated the role of ubiquitin-specific protease (USP) 11 in colorectal cancer (CRC) pathogenesis. RNA-seq analysis of tumor and matched normal tissues from 35 CRC patients identified USP11 as significantly overexpressed in tumor samples.