NLRP3 Facilitates α-Synuclein-Induced Dopaminergic Neuronal Senescence in a Mouse Model of Parkinson’s Disease through SATB1/DNA Damage/P21 Signaling Pathway

Scientists identified the cell type susceptible to α-synuclein-induced cellular senescence in the substantia nigra and investigated the specific role of microglia with a particular focus on the NLRP3 inflammasome.