Positive Feedback Regulation between USP8 and Hippo/YAP Axis Drives Triple-Negative Breast Cancer Progression

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Researchers revealed a forward feedback loop between Ubiquitin Specific Peptidase 8 (USP8) and Hippo signaling in TNBC, indicating USP8 as a potential therapeutic drug targets in TNBC.
[Cell Death & Disease]
Abstract