LDB1 Regulates Gene Expression and Chromatin Structure in Pluripotency and Lineage Differentiation

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Researchers generated LIM domain-binding 1 (Ldb1)(-/-) ESCs using CRISPR/Cas9 editing and observed a reduction in key stem cell factors SOX2 and KLF4 upon LDB1 loss.
[Nucleic Acids Research]
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