Histone Demethylase KDM7A Negatively Regulates Fibrotic Macrophage Polarization and Lung Fibrosis Progression

Researchers uncovered an epigenetic mechanism restraining disease-driving macrophage states and suggest the lysine-specific demethylase 7 A (KDM7A)-toll-like receptor 8 axis as a potential therapeutic target in fibrotic disorders.