Mesenchymal Stem Cells Alleviate Experimental Cerebral Malaria Disease Severity by Inducing RoRγT+ Foxp3+ T Regulatory (Tr 17) Cells and Modulating the Dysregulated Th17/Treg Axis

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The authors investigated the therapeutic potential of MSCs in managing the excess proinflammatory response and maintaining immune homeostasis in Plasmodium berghei ANKA infected C57BL/6 mice, an experimental cerebral malaria disease model.
[Cell Death Discovery]
AbstractGraphical Abstract