MAGE-A4 pMHC-Targeted CAR-T Cells Exploiting TCR Machinery Exhibit Significantly Improved In Vivo Function While Retaining Antigen Specificity

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Researchers determined whether MAGE-A4 pMHC-targeted CAR-T cells using the T cell receptor machinery exhibited superior functionality without compromising antigen specificity.
[Journal of Immunotherapy of Cancer]
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