NewslettersUmbilical & Placental Cell NewsMolecular Regulation of Trophoblast Stem Cell Self-Renewal and Giant Cell Differentiation by the Hippo Components YAP and LATS1By Britya Ghosh - May 12, 20220331Trophoblast giant cells differentiation is associated with cytoplasmic retention of YAP, heightened pYAPSer127, decrease in the level of the core Hippo component, LATS1, which thereby impedes LATS1-LIMK2 association.[Stem Cell Research & Therapy]Full Article