Molecular Regulation of Trophoblast Stem Cell Self-Renewal and Giant Cell Differentiation by the Hippo Components YAP and LATS1
Trophoblast giant cells differentiation is associated with cytoplasmic retention of YAP, heightened pYAPSer127, decrease in the level of the core Hippo component, LATS1, which thereby impedes LATS1-LIMK2 association.
[Nature News] A highly infectious and deadly strain of avian influenza virus has infected tens of millions of poultry birds across Europe, Asia, Africa and North America. But scientists are particularly concerned about the unprecedented spread in wild birds.
[Science of the Total Environment] By exposing human intestinal organoids to polystyrene nanoplastics with concentrations of 10 and 100 μg/mL, scientists presented evidence of their distinct accumulation in various type cells in intestinal organoids, then causing the cell apoptosis and inflammatory response.