The authors review the molecular mechanisms that enable cancer cells to switch from an androgen receptor (AR)-positive to an AR-negative disease and efforts to prevent/revert this process and thereby maintain/restore AR-dependence.
[Oncogene]
Formaggio, N., Rubin, M. A., & Theurillat, J.-P. (2021). Loss and revival of androgen receptor signaling in advanced prostate cancer. Oncogene, 1–12. https://doi.org/10.1038/s41388-020-01598-0 Cite
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