AR and ERG Drive the Expression of Prostate Cancer Specific Long Noncoding RNAs

In vitro validations confirmed that androgen receptor and ETS-related gene (ERG) regulated a subset of TPCATs, most notably for EPCART.
[Oncogene]
[zotpress userid=’6445218 items=’5SUP85V4′ style=’apa’ cite=’yes’]
Abstract
Bookmark

No account yet? Register

Share

KLF5 Inhibits STAT3 Activity and Tumor Metastasis in Prostate Cancer by Suppressing IGF1 Transcription Cooperatively with HDAC1

Scientists knocked down KLF5 in prostate cancer cells and found that KLF5 knockdown promoted invasive ability of prostate cancer cells in vitro and in vivo .
[Cell Death & Disease]
[zotpress userid=’6445218 items=’MHPK6Q5N’ style=’apa’ cite=’yes’]
Full Article
Bookmark

No account yet? Register

Share

Dehydrozingerone, a Curcumin Analog, as a Potential Anti-Prostate Cancer Inhibitor In Vitro and In Vivo

The authors revealed that dehydrozingerone decreased cell proliferation of rat castration-resistant prostate cancer, PLS10 cells, via induction of the cell cycle arrest in the G1 phase in vitro.
[Molecules]
[zotpress userid=’6445218 items=’EUGHUCNG’ style=’apa’ cite=’yes’]
Full Article
Bookmark

No account yet? Register

Share

Effect of Palmitic Acid on Exosome-Mediated Secretion and Invasive Motility in Prostate Cancer Cells

Palmitic acid decreased the secretion of exosomes in human prostate cancer cells in vitro in a concentration-dependent manner.
[Molecules]
[zotpress userid=’6445218 items=’Y7WEFEAT’ style=’apa’ cite=’yes’]
Full Article
Bookmark

No account yet? Register

Share

Androgens Modify Therapeutic Response to Cabazitaxel in Models of Advanced Prostate Cancer

To examine the impact of androgens on the antitumor effect of cabazitaxel (CBZ), investigators used human prostate cancer cell lines with different sensitivity to androgens and CBZ.
[Prostate]
[zotpress userid=’6445218 items=’QWT5XLBG’ style=’apa’ cite=’yes’]
Abstract
Bookmark

No account yet? Register

Share

Resveratrol Inhibits the Tumor Migration and Invasion by Upregulating TET1 and Reducing TIMP2/3 Methylation in Prostate Carcinoma Cells

Resveratrol inhibited the migration and invasion of prostate cancer cells, promoted the demethylation of tissue inhibitor of metalloproteinases (TIMP)2 and TIMP3 to upregulate their expressions, and suppressed the expressions of MMP2 and MMP9.
[Prostate]
[zotpress userid=’6445218′ items=’LE93QR7J’ style=’apa’ cite=’yes’]
Abstract
Bookmark

No account yet? Register

Share

Altered Staining Patterns and Expression Level of Engrailed-2 in Benign Prostatic Hyperplasia and Prostate Cancer Predict Prostatic Disease Progression

Scientists showed that their homemade engrailed-2 (EN2) monoclonal antibody could specifically bind endogenous and exogenous EN2 protein in three different prostate cancer cell lines.
[BMC Cancer]
[zotpress userid=’6445218 items=’FYCYV4A9′ style=’apa’ cite=’yes’]
Full Article
Bookmark

No account yet? Register

Share

The miR-1908/SRM Regulatory Axis Contributes to Extracellular Vesicle Secretion in Prostate Cancer

Researchers investigated the target genes of miR-1908 by siRNA screening and identified that spermidine synthase was the key regulator of extracellular vesicle secretion in 22Rv1 cells.
[Cancer Science]
[zotpress userid=’6445218 items=’BWR5QBNH’ style=’apa’ cite=’yes’]
Abstract
Bookmark

No account yet? Register

Share

Novel Long Non-Coding RNA lncAMPC Promotes Metastasis and Immunosuppression in Prostate Cancer by Stimulating LIF/LIFR Expression

The biological capacity of lncRNA named lncRNA activated in metastatic PCa (lncAMPC) in prostate cancer (PCa) was demonstrated both in vitro and in vivo. The lncAMPC was overexpressed in tumor tissue and urine of metastatic PCa patients and promoted PCa tumorigenesis and metastasis.
[Molecular Therapy]
[zotpress items='{6445212:D4ACK2C8}’ style=’apa’ cite=’yes’]
AbstractGraphical Abstract
Bookmark

No account yet? Register

Share

Huge Open-Access Journal Deal Inked by University of California and Springer Nature

The University of California (UC) system announced it has signed the biggest open-access deal in North America with one of the largest commercial scientific publishers. The agreement with Springer Nature includes a commitment by the publisher to explore making all articles that UC corresponding authors publish in the Nature family of journals immediately free to read on publication starting in 2022.
[ScienceInsider]
Editorial
Bookmark

No account yet? Register

Share
Share