β-cells

[ACS Nano] Investigators described a strategy that utilizes pretargeting and glycochemistry to bioengineer β cells in situ to induce β-cell-specific tolerance.

[FEBS Journal] Investigators found that the RIIB subunit of protein kinase A is expressed specifically by β cells of mouse and human islets.

[Endocrine] Regeneration proceedings for pancreatic β cells are promising and could improve β-cell proliferation capacity and contribute to the conservation of mature β-cell phenotypic characteristics.

[Cell Reports] Investigators demonstrated that Tentonin 3/TMEM150C, a mechanosensitive channel, contributes to glucose-stimulated insulin secretion by mediating cation influx.

[Journal of Physiology] Using a comprehensive combination of genetically modified fish, electrophysiology, and gene expression analysis, scientists demonstrated that zebra fish cardiac myocytes and vascular smooth muscle expressed functional ATP-sensitive potassium channels channels of similar subunit composition, structure, and metabolic sensitivity to their mammalian counterparts.

[Biomedicine & Pharmacotherapy] The authors isolated pancreatic islets from adult male Wistar rats and identified pancreatic β-cells by the cell size, capacitance and membrane potential.