AKT

[Bioengineered] Researchers explored the potential mechanism of exosome-derived miR-631 targeting and regulating E2F family of transcription factor 2 to repress the malignant behavior of NSCLC cells.

[Cell Death & Disease] Phenotypic and metabolic profiles with associated cellular signaling pathways involved in lipid metabolism were investigated in the mice heart and human cardiomyocytes to establish treatment effect of adiponectin's agonists.

[Oxidative Medicine and Cellular Longevity] Scientists explored the effect of the plasma-activated medium on lung cancer cells in vitro and in vivo by using a 3D cell culture model.

[Inflammation Research] Scientists demonstrated the protective role of Insulin-like growth factor 1 (IGF-1) against pancreatic β cell dysfunction and to probe into the underlying mechanisms.

[Journal of Controlled Release] Scientists found that exosomes from primary brain tumors could upregulate the expression of lipocalin-2 in bEnd.3 brain microvascular endothelial cells

[Hepatology] Researchers performed single-cell RNA-sequencing using AKT/NICD-induced mouse intrahepatic cholangiocarcinoma tissues at early, middle, and late stages.