AMPK

[Cell Death & Disease] Investigators found that interference with GPR120 activity using pharmacological agonist attenuated the severity of the liver injury and mortality of fulminant hepatic failure in mice.

[Evidence-Based Complementary and Alternative Medicine] The expression level of relative proteins in mTOR pathway was detected by western blot assay to investigate the mechanism of Qingjie Fuzheng granule effect on colorectal cancer cells.

[Scientific Reports] The authors investigated miR1908-5p function by leveraging human primary hepatocytes and HuH-7 hepatoma models and implicated miR1908-5p in metabolic and energy regulation in hepatocyte models via multiple, independent, pathways.

[Communications Biology] In iPSC-derived retinal pigment epithelium from late-onset retinal degeneration patients, researchers showed that the dominant pathogenic CTRP5 variant led to reduced CTRP5 secretion.

[Scientific Reports] The authors found that a small molecule phenylbutenoid dimer NMac1, a previously identified anti-metastatic agent, had novel anti-proliferative effect only under glucose starvation in metastatic breast cancer cells.

[Molecular Immunology] Researchers investigated whether Omarigliptin possessed a beneficial effect against LPS-induced injuries in human BEAS-2B bronchial epithelial cells.