Tag results:

ASC

Povidone Iodine Suppresses LPS-Induced Inflammation by Inhibiting TLR4/MyD88 Formation in Airway Epithelial Cells

[Scientific Reports] The authors explored the anti-inflammatory effects and underlying molecular mechanism of povidone-iodine (PVP-I) on lipopolysaccharide-stimulated airway epithelial cells and investigated whether nasal instillation of PVP-I could suppress mucosal inflammation in non-eosinophilic chronic rhinosinusitis mice.

Zhilong Huoxue Tongyu Capsule Alleviated the Pyroptosis of Vascular Endothelial Cells Induced by Ox-LDL through miR-30b-5p/NLRP3

[Evidence-Based Complementary and Alternative Medicine] Human coronary artery endothelial cells were induced with oxidized low-density lipoprotein to obtain cellular atherosclerosis models.

NLRP3 Inflammasome Activation in Human Peripheral Blood Mononuclear Cells Induced by Venoms Secreted PLAM2s

[International Journal of Biological Macromolecules] Peripheral blood mononuclear cells were isolated by density gradient and incubated with RPMI, LPS, BthTX-I or BthTX-II isolated from Bothrops jararacussu venom, to evaluate viability, and the results showed that there was no cell death.

LncRNA ROR Modulates Myocardial Ischemia-Reperfusion Injury Mediated by the miR-185-5p/CDK6 Axis

[Laboratory Investigation] Researchers revealed that hypoxia/reoxygenation (H/R) treated human cardiac myocytes showed a significantly decreased miR-185-5p expression and increased expression of CDK6 and ROR.

Downregulating Expression of OPTN Elevates Neuroinflammation via AIM2 Inflammasome- and RIPK1-Activating Mechanisms in APP/PS1 Transgenic Mice

[Journal of Neuroinflammation] Neuroinflammation is thought to be a cause of Alzheimer’s disease (AD), which is partly caused by inadequate mitophagy. As a receptor of mitophagy, the authors revealed the regulatory roles of optineurin (OPTN) on neuroinflammation in the pathogenesis of AD.

Robust Immune Responses Are Observed after One Dose of BNT162b2 mRNA Vaccine Dose in SARS-CoV-2 Experienced Individuals

[Science Translational Medicine] Scientists evaluated longitudinal immune responses to two-dose BNT162b2 mRNA vaccination in 15 adults who had experienced COVID-19, compared to 21 adults who did not have prior COVID-19.

Popular