B cells

[Science Translational Medicine] The authors showed that multiple carcinomas expressed extracellular N-glycans, whose abundance negatively correlated with CAR T cell killing.

[Blood Advances] Researchers examined whether serum levels of neurofilament light chain, a marker of neuroaxonal injury, correlated with the severity of immune effector cell-associated neurotoxicity syndrome.

[Journal of Immunology] Researchers generated a NOD congenic mouse bearing B10 resistance alleles on chromosome 9 in a locus coinciding with part of the insulin-dependent diabetes (Idd) locus and found that NOD.

[Leukemia] To mitigate antigen escape and potentially improve the durability of remission, scientists developed a dual-targeting approach using an optimized, bispecific CAR construct that targets both CD19 and BAFF-R.

[Pediatric Research] Fetal B-1 and B-2 B cells involved in innate and adaptive immune responses, respectively, arise in staggered waves of development from distinct progenitors.

[IMV Inc.] IMV, Inc., a clinical-stage company developing a portfolio of immune-educating therapies based on its novel DPX platform to treat solid and hematologic cancers, announced a first patient dosed in the VITALIZE Phase IIB clinical trial.