B cells

[Nature Communications] Investigators developed a B cell-activating factor (BAFF) ligand-based CAR and generated BAFF CAR-T cells using a non-viral gene delivery method.

[Journal of Experimental Medicine] Scientists review recent efforts to gain a better molecular and cellular understanding of anti-Plasmodium falciparum circumsporozoite protein B cell responses in humans and discuss ways to overcome limitations in the induction of stable titers of high-affinity antibodies.

[Frontiers in Immunology] According to large-scale single-cell analysis, recovered patients, who had severe symptoms, still exhibited peripheral immune disorders one-two months after symptom onset.

[Genome Medicine] Scientists adapted a B cell pipeline for undocumented alleles, genotype, and haplotype inference for full and partial adaptive immune receptor repertoire sequencing T cell receptor data sets.

[Proceedings of the National Academy of Sciences of the United States of America] A strong response was induced in monocytes and B cells, with a SARS-CoV-2–specific inflammatory gene cluster distinct from that seen in influenza A or Ebola virus-infected cocultures, and which reproduced deviations reported in blood or lung myeloid cells from COVID-19 patients.

[Scientific Reports] Researchers reported the design of a multi-epitope vaccine against Hemagglutinin and Neuraminidase proteins of H7N9 Influenza A virus by prediction of Cytotoxic T lymphocyte, Helper T lymphocyte, IFN-γ and B cell epitopes.