Bcl-2

[Bioengineered] Researchers indicated that circ_0001679/miR-338-3p/MAPK1 axis may play an important role in the pathogenesis of acute lung injury.

[Nature Medicine] Through integrative molecular profiling of HSCs and progenitor cells in large patient cohorts, scientists found that myelodysplastic syndromes HSCs in two distinct differentiation states were maintained throughout the clinical course of the disease.

[Molecular Biotechnology] Researchers probe the role of Sox9 in cardiomyocyte apoptosis after acute myocardial infarction (AMI). AMI cell model was established in AC16 cells by hypoxia treatment.

[Toxicology and Applied Pharmacology] The authors determined the role of the 5-HT degradation system in mitochondrial damage and apoptosis of hepatocytes.

[Journal of Biomedical Science] Combination treatment of docetaxel with caffeic acid phenethyl ester effectively suppressed the proliferation and survival of docetaxel-resistant prostate cancer cells via inhibition of Bcl-2 and c-Myc as well as induction of metabolism interference.

[Scientific Reports] RNA-seq analysis revealed that differentially expressed genes in the C57 healing tendon at 7 days post injury were functionally linked to fibrosis, immune system signaling and ECM organization, while the differentially expressed genes in the Murphy Roth’s Large (MRL) mouse injured tendon were dominated by cell cycle pathways.