CD133

[Stem Cells] Scientists suggested that the asymmetric distribution of pericentrosomal CD133 endosomes induced the symmetry breaking of autophagic activity during cytokinesis in cooperation with nuclear β-catenin.

[Histology and Histopathology] To elucidate tumor cell behavior associated with CSC marker expression, the expression of CD133, CD44v9, and ALDH1A1, which are considered markers of CSCs, was examined in sporadic and ulcerative colitis-associated colorectal tumors.

[Small] The authors found that gelatin methacryloyl (GelMA)-nanoclay hybrid hydrogels could induce and enrich colorectal cancer stem cells assisted by three-dimensional bioprinting.

[Cell Cycle] Scientists investigated the effect of LINC01234 on the differentiation and self-renewal of ovarian cancer stem cells through adsorption of microRNA-27b-5p to target sirtuins 5 (SIRT5).

[Cellular and Molecular Life Sciences] The in vitro and in vivo results indicated that CD133+ stem cell-like cells are the main subpopulation and PARP1 was the central gene mediating oxaliplatin resistance in gastric cancer.

[Frontiers in Bioscience-Landmark] Using flow cytometry and western blot assays, the authors have demonstrated that programmed cell death ligand 1 expression is higher in endometrial cancer stem-like cell derived from endometrial cancer than in nonstem-like cancer cells.