CD133

[Skin Pharmacology and Physiology] Scientists assessed the effect of metformin on hair growth in a mouse hair follicle reconstitution model generated by in vitro self-assembled 3D aggregates of epidermal and dermal cells and suggested that metformin could promote hair follicle regeneration through up-regulation of the hair inductive capability of dermal cells.

[Laboratory Investigation] Investigators used a barcode labelling approach of glioma-initiating cells to generate clonal populations over a number of passages, in combination with phenotyping using the established stem cell markers CD133, CD15, CD44, and A2B5.

[Journal of Immunology Research] Scientists explored the differentially expressed miRNAs related to tumor cell-derived extracellular vesciles (EVs) and the mechanism by which EVs regulated hepatoblastoma progression.

[Biotechnology Progress] Scientists examined the importance of hypoxia-preconditioned mesenchymal stem cells-derived exosomes and normoxia-preconditioned MSC-derived exosomes in the self-renewal and long-term clonogenic potential of umbilical cord blood hematopoietic stem cells.

[Cell Death Discovery] The authors found that the stemness characteristics of lung cancer cells were significantly enhanced by the overexpression of non-muscle myosin heavy chain 9 (MYH9), and the knockout of MYH9 had the opposite effects.

[Cell Death & Disease] Researchers studied the role of the Par3 protein (encoded by PARD3) in glioblastoma multiforme (GBM). GBM patient transcriptomic data and patient-derived culture analysis indicated diverse levels of expression of PARD3 across and independent from subtypes