CD133

[Biomedicine & Pharmacotherapy] Anti-carcinogenic properties of amorphous curcumin, a compound with improved solubility and bioavailability, were evaluated against human colorectal cancer organoids.

[Stem Cells and Development] Compared with tumor-adjacent normal tissues, death-associated protein kinase 1 (DAPK1) expression was reduced in prostate cancer cell lines with respect to that in normal prostate cells.

[Thrombosis Research] Scientists characterized the mechanisms behind prostate CSC-platelet interaction. Fluorescence Activated Cell Sorting was utilized to separate DU145 and PC3 prostate cancer cells into CD133+/CD44+, CD133+/CD44-, CD44+/CD133-, and CD133-/CD44- subpopulations and to measure their CXCR4 surface expression.

[Surgery] Expression of CSC markers was examined in 572 thyroid tumors from The Cancer Genome Atlas Thyroid Cancer database and tall cell variant and papillary thyroid carcinoma tumors by immunohistochemistry.

[Experimental Biology and Medicine] The authors demonstrated significant overexpression of ONECUT2 and down-regulation of hsa-miR-15a-5p in gastric cancer via bioinformatics analysis and in vitro assays.

[Diabetologia] The authors investigated whether fenofibrate increased circulating hematopoietic stem/progenitor cells (HSPCs). When compared with placebo, fenofibrate significantly increased levels of HSPCs expressing CD34 and/or CD133.