Osteogenic and Angiogenic Profiles of the Palatal Process of the Maxilla and the Palatal Process of the Palatine Bone

The authors found that the period in which avascular mesenchymal condensation became a vascularized bone structure corresponded to embryonic day 14.5 to embyronic day 16.5 in the hard palate.
[Journal of Anatomy]
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Co-Delivery of Fibrin-Laminin Hydrogel with Mesenchymal Stem Cell Spheroids Supports Skeletal Muscle Regeneration Following Trauma

MSC aggregation into spheroids was optimized in vitro based on cellular viability, spheroid size, and trophic factor secretion. The regenerative potential of the optimized MSC spheroid therapy was then investigated in a murine model of volumetric muscle loss injury.
[Tissue Engineering and Regenerative Medicine]
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Role of Aneuploid Circulating Tumor Cells and CD31+ Circulating Tumor Endothelial Cells in Predicting and Monitoring Anti-angiogenic Therapy Efficacy in Advanced NSCLC

Co-detection and comprehensive phenotypic and karyotypic molecular characterization of aneuploid circulating tumor cells and circulating tumor endothelial cells were conducted on non-small cell lung cancer patients receiving bevacizumab plus chemotherapy.
[Molecular Oncology]
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Dual Effects of Atorvastatin on Angiogenesis Pathways in the Differentiation of Mesenchymal Stem Cells

Researchers studied atorvastatin effects on the angiogenesis-signaling pathways from MSCs’ differentiation to tissue angiogenesis.
[European Journal of Pharmacology]
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Inverse and Reciprocal Regulation of p53/p21 and BMI-1 Modulates Vasculogenic Differentiation of Dental Pulp Stem Cells

Dental pulp stem cells seeded in biodegradable scaffolds and transplanted into immunodeficient mice generated mature human blood vessels invested with smooth muscle actin-positive mural cells.
[Cell Death & Disease]
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Hyperbaric Oxygen Suppressed Tumor Progression through the Improvement of Tumor Hypoxia and Induction of Tumor Apoptosis in A549-Cell-Transferred Lung Cancer

Reserachers investigated the effects of hyperbaric oxygen treatment (HBOT) on solid tumors, such as lung cancer. Non-small cell human lung carcinoma A549-cell-transferred severe combined immunodeficiency mice were selected as an in vivo model to detect the potential mechanism of HBOT in lung tumors.
[Scientific Reports]
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Matrigel/Umbilical Cord-Derived Mesenchymal Stem Cells Promote Granulosa Cell Proliferation and Ovarian Vascularization in a Mouse Model of Premature Ovarian Failure

Investigators aimed to fabricate a Matrigel scaffold loaded with human umbilical cord-derived MSCs and explore its potential to restore ovarian function and repair ovarian structures in vitro and in vivo.
[Stem Cells and Development]
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LncRNA MAGI2-AS3 Inhibits Tumor Progression and Angiogenesis by Regulating ACY1 via Interacting with Transcription Factor HEY1 in Clear Cell Renal Cell Carcinoma

Angiogenesis was evaluated in the Matrigel-based human umbilical vein endothelial cell-RLC-310 coculture model and immunohistochemical staining for vascular endothelial growth factor and CD31 in tumor tissues collected from a xenograft ccRCC mouse model.
[Cancer Gene Therapy]
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Knockout RAGE Alleviates Cardiac Fibrosis through Repressing Endothelial-to-Mesenchymal Transition (EndMT) Mediated by Autophagy

Scientists found a decrease in endothelial cells and an increase in cells co-expressing CD31 and α-smooth muscle actin at eight weeks in heart tissue of mice subjected to transverse aortic constriction, which implied EndMT.
[Cell Death & Disease]
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Fabrication of Vascularized DPSC Constructs for Efficient Pulp Regeneration

Vascularized dental pulp stem cells (DPSC) constructs were fabricated by inducing endothelial differentiation, and then scientist investigated the behavior of differentiated DPSCs, the internal structure of cell constructs, and their pulp regenerative ability in vivo.
[Journal of Dental Research]
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MiR-205-5p Suppresses Angiogenesis in Gastric Cancer by Downregulating the Expression of VEGFA and FGF1

To help identify new strategies for antiangiogenic therapy in gastric cancer (GC), scientists evaluated miR-205-5p expression in GC tissues from TCGA database and our hospital, and its functions in angiogenesis were explored in vitro and in vivo.
[Experimental Cell Research]
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