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CD69

The Development of Chiral Nanoparticles to Target NK Cells and CD8+ T Cells for Cancer Immunotherapy

[Advanced Materials] Researchers investigated the immunological effect of chiral nanomaterials as therapeutic and preventive options against tumors.

Spatial, Temporal and Molecular Dynamics of Swine Influenza Virus-Specific CD8 Tissue Resident Memory T Cells

[Mucosal Immunology] Most nucleoprotein-specific CD8 T cells in broncho-alveolar lavage and lung are tissue resident memory cells that express CD69 and downregulate CD45RA and CCR7.

Differential Localization and Limited Cytotoxic Potential of Duodenal CD8+ T Cells

[JCI Insight] Scientists examined the spatial localization, phenotype, and function of CD8+ T cells in the human duodenal tissue from people living with HIV and healthy controls.

Lung-Resident Memory B Cells Established after Pulmonary Influenza Infection Display Distinct Transcriptional and Phenotypic Profiles

[Science Immunology] Scientists characterized tissue-resident memory B cells that were stably maintained in the lungs of mice after pulmonary influenza infection.

Single‐Cell Immune Mapping of Melanoma Sentinel Lymph Nodes Reveals an Actionable Immunotolerant Microenvironment

[Clinical Cancer Research] Researchers used mass cytometry by time-of-flight, flow cytometry, and T cell receptor immunosequencing to conduct simultaneous single-cell analyses of immune cells in the sentinel lymph nodes of melanoma patients.

A BAFF Ligand-Based CAR-T Cell Targeting Three Receptors and Multiple B Cell Cancers

[Nature Communications] Investigators developed a B cell-activating factor (BAFF) ligand-based CAR and generated BAFF CAR-T cells using a non-viral gene delivery method.

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