CD69

[Frontiers in Immunology] According to large-scale single-cell analysis, recovered patients, who had severe symptoms, still exhibited peripheral immune disorders one-two months after symptom onset.

[Nature Communications] Using multiplex immunofluorescence staining in cohorts of anti-PD-1 and anti-PD-L1-treated lung cancer patients, scientists showed that decreased expression of cancer cell αV was associated with improved immunotherapy-related, progression-free survival.

[Nature Communications] Single-cell transcriptome analysis and FACS analysis revealed CD69+CD103−CD8+ Trm cell enrichment in non-alcoholic steatohepatitis resolution livers.

[Stroke] Lymphocytes from Nur77GFP transgenic mice express a fluorescent protein upon activation via the TCR, allowing the differentiation of activation mode in a natural repertoire of immune cells and antigens.

[European Journal of Immunology] Researchers reported a direct comparison of E2- and P4-mediated effects on human CD4+ T cells, key cells in immune regulation. T cells were stimulated to obtain different levels of activation and exposed to a broad range of hormone concentrations.

[Science Translational Medicine] By combining endoscopy-guided sampling of the biliary tree with a high-dimensional analysis approach, comprehensive mapping of the human biliary immunological landscape in patients with primary sclerosing cholangitis, a severe biliary inflammatory disease, was conducted.