CD8

[Clinical and Translational Oncology] Pretreated specimens were evaluated by immunohistochemistry for programmed cell death protein 1 and its ligand, densities of tumor infiltrative lymphocytes, as well as c-MYC and Ki-67 expressions.

[Cell Reports] The authors observed distinct locations for parasite-specific T cell subsets, implying a link between differentiation and anatomical niches in the spleen.

[Cell] Low serum magnesium levels were associated with more rapid disease progression and shorter overall survival in CAR T cell and immune checkpoint antibody-treated patients.

[Journal of Experimental Medicine] Using single-cell transcriptomics and T cell receptor sequencing, scientists analyzed mononuclear cell populations in paired pleural fluid and peripheral blood of tuberculous pleural effusion patients.

[Cell] In subjects ∼6 months post-vaccination, 90% and 87% of memory T cell responses were preserved against variants on average by AIM assay, and 84% and 85% preserved against Omicron.

[Nature Communications] Investigators used multi-omics single-cell analysis to probe the dynamic immune responses in hospitalized patients with stable or progressive course of COVID-19, explore V(D)J repertoires, and assess the cellular effects of tocilizumab.