EMT

[Cell & Bioscience] The authors revealed the potential mechanisms of which GV1001-stimulated Gαs-cAMP signaling pathway reduced the migration and metastasis of prostate cancer cells.

[Medical Oncology] Scientists reported that although silencing Akt1 enhanced the invasion of prostate cancer (PCa) cells induced by nutritional starvation (NST) in vitro, silencing Akt1 inhibited the PCa lung metastasis induced by NST in vivo.

[Oncogenesis] Scientists showed that FATP5 was downregulated in hepatocellular carcinoma tissues and even much lower in vascular tumor thrombi.

[Journal of Controlled Release] Investigators engineered a photodynamic nanoplatform to manipulate breast cancer stem cells against tumor progression and metastasis by not only remolding the disequilibrium state but also blocking the epithelial-mesenchymal transition process.

[Journal of Materials Chemistry B] The authors observed that prostate cancer cells and breast cancer cells cultured with nanodiamonds showed morphological changes and altered gene and protein expression.

[Cell Death Discovery] Researchers revealed that F-box and leucine-rich repeat protein 10 (FBXL10) served as a pro-metastatic factor in breast cancer via repressing the expression of E-cadherin and inducing epithelial-mesenchymal transition (EMT).