EMT

[Oncogene] Scientists showed that a majority of human melanoma overexpressed discoidin domain receptor 2 after treatment.

[Journal of Cancer Research and Clinical Oncology] The authors assessed the function of KMT2C in prostate cancer cell proliferation, colony formation, and migration.

[Phytomedicine] Researchers employed MiaPaCa-2 and PANC-1 cell lines and investigated how urokinase-plasmin activator (uPA) regulated epithelial-mesenchymal transition and metastasis in pancreatic cancer, and presented a novel approach aimed at inhibiting uPA in pancreatic cancer.

[Asian Journal of Andrology] Scientists identified downregulated long noncoding RNA (lncRNA) growth arrest-specific 5 (GAS5) in prostate cancer that was associated with metastasis and paclitaxel resistance.

[Frontiers in Molecular Biosciences] In vitro genetic ablation of golgi phosphoprotein 3 (GOLPH3) was performed using small interfering RNA transfection, and a stably overexpressed GOLPH3 colon cancer cell line was constructed using the lentivirus system.

[Molecular Therapy Oncolytics] MicroRNAs (MiRNAs) that targeted ADP-ribosylation factor 6 (ARF6) were predicted and selected in high metastatic breast cancer cells treated with C–C motif chemokine ligand 18 (CCL18).