FACS

[Cell Proliferation] Scientists showed that retinoic acid had a broader role in 2C‐like cells state, not only was one of the upstream regulators of the 2C‐like state in chemically defined media but also illuminated genetic and epigenetic regulations that govern ESCs to 2C‐like transition.

[Scientific Reports] Researchers found that lymphangioleiomyomatosi - affected lung tissues (LAM-LECs) had significantly higher ability of proliferation and migration compared to control LECs.

[Scientific Reports] Hhuman primary-cultured lymphatic endothelial cells were obtained both from lymphangioleiomyomatosis-affected lung tissues and normal lung tissues using fluorescence-activated cell sorting.

[Molecular Metabolism] Time-lapse studies of organoids from Trpm5GFP:Gpr64mCherry mice revealed sequential expression of initially Trpm5GFP and subsequently also Gpr64mCherry in maturing intestinal tuft cells.

[Gastroenterology] Scientists demonstrated that Bcl3 impacted pancreatic carcinogenesis by restraining cancer stem cell expansion and by curtailing an aggressive and metastatic tumor burden in pancreatic ductal adenocarcinoma across species.

[Stem Cell Research & Therapy] Transplantation of the hiPSC-derived neural crest cells rapidly restored rabbit corneal thickness and clarity. However, the long-term recovery efficacy was impaired by the improper maturation, senescence, and endothelial-mesenchymal transition of the transplanted cells.