FACS

[Molecular Cancer Research] CRISPR-Cas9 and shRNA were used to eliminate TFAP2A expression in HCT116 and a panel of colon cancer cell lines.

[Circulation] Epicardial-derived cardiac fibroblasts and epithelial cells express paracrine factors, including TGFβ1 and FGFs, which mediate EMT, and contribute to the pathogenesis of myocardial fibrosis, apoptosis, arrhythmias, and cardiac dysfunction in a mouse model of arrhythmogenic cardiomyopathy.

[eLife] Scientists applied florescence-activated cell sorting, RNA sequencing and bioinformatic methods to investigate the common effects of cardiovascular disease risk factors in mouse cardiac endothelial cells.

[Cell Death Discovery] In multiple cell lines, the overexpression of BMP4 increased the expression of Alzheimer’s disease-related proteins, whereas the downregulation of BMP4 demonstrated opposing effects.

[Scientific Reports] The authors report that the human mesenchymal stem cell (hMSC) secretome increased the proliferation of human granulosa cells (HGrC1). They showed by FACS analysis that treatment of HGrC1 cells with hMSC-conditioned media stimulated cellular proliferation.

[Translational Oncology] Prostate-specific antigen (PSA)+ and PSA−/lo cells were successfully separated from LNCaP xenograft tumors after prostate- PSAP-GFP vector infection and FACS.