Fos

[PLoS Biology] Investigators found that the tissue invasion of Drosophila macrophages, also known as plasmatocytes or hemocytes, utilized enhanced cortical F-actin levels stimulated by the Drosophila member of the fos proto oncogene transcription factor family.

[Scientific Reports] Researchers identified differentially expressed genes via a comparison between luminal A breast cancer subtypes and normal mammary ductal cells from healthy donors.

[Cell Reports] Researchers used surface markers of resistant basal cell carcinomas and patient single-cell and bulk transcriptomic data, and uncovered the dynamic roadmap of basal to squamous cell carcinoma transition.

[Cell Reports] The authors revealed that the immune-specific transmembrane adaptor SCIMP was a direct scaffold for Erk1/2 in TLR pathways, with high-resolution, live-cell imaging revealing that SCIMP guided the spatial and temporal recruitment of Erk2 to membrane ruffles and macropinosomes for pro-inflammatory TLR4 signaling.

[Biochemical Pharmacology] The authors investigated the intracellular signaling pathway following stimulation of Cav1.2 Ca2+ channels and addressed the function of the transcription factor activator protein-1 in pancreatic β-cells of transgenic mice.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers found that except for SP1, the other tethering partners of ERβ (Fos, Jun, Fra1) were down-regulated in TNBC, meaning that the tumor-suppressive functions of ERβ were severely compromised.