Researchers suggested that Muse cells homed in a lesion site-dependent manner and protected the spinal cord against motor neuron death. Muse cells might also be a promising cell source for the treatment of amyotrophic lateral sclerosis patients.
Yamashita, T., Kushida, Y., Wakao, S., Tadokoro, K., Nomura, E., Omote, Y., Takemoto, M., Hishikawa, N., Ohta, Y., Dezawa, M., & Abe, K. (2020). Therapeutic benefit of Muse cells in a mouse model of amyotrophic lateral sclerosis. Scientific Reports, 10(1), 17102. https://doi.org/10.1038/s41598-020-74216-4Cite
Scientists examined whether epidermal growth factor receptor (EGFR) signaling affects bone morphogenic protein 4-induced differentiation of glioma stem cells and their response to the alkylating drug temozolomide.