HIV

[Molecular Cancer Research] Vpr binding protein (VPRBP) knockdown in prostate cancer cells led to a significant decrease in cell proliferation, p53 stabilization, nucleolar fragmentation and increased p53 recruitment to the chromatin.

[Clinical Immunology] Mass cytometry and high-throughput sequencing of the T cell receptor were used to profile the host immune response to HIV-1 and P. jirovecii infection.

[Immunity] Researchers used single-cell ECCITE-seq, which captures surface protein expression, cellular transcriptome, HIV-1 RNA, and TCR sequences within the same single cell to track clonal expansion dynamics in longitudinally archived samples from six HIV-1-infected individuals and two uninfected individuals.

[Enochian BioSciences] Enochian BioSciences issued an exclusive sub-license of one of its proprietary technologies that could improve the effectiveness of a potential cure for HIV with an anti-HIV CAR-T therapy that Caring Cross is studying in a clinical trial.

[NatureNews] Adding to the brutal, immediate effects of Russia’s invasion, the Ukrainian people are facing an onslaught of infectious diseases. Some threats — such as the spread of COVID-19 — are immediate, as people huddle in basements, subway stations and temporary shelters to protect themselves from bombardments.

[BMC Infectious Diseases] A survey was conducted in men from an HIV cohort in Taizhou, China between 2016 and 2019. A face-to-face questionnaire interview was administered, and an anal-canal swab was collected for HPV genotyping.