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HUVECs

Mimicking Native Liver Lobule Microarchitecture In Vitro with Parenchymal and Non-Parenchymal Cells Using 3D Bioprinting for Drug Toxicity and Drug Screening Applications

[ACS Applied Materials & interfaces] A physiologically relevant human vascularized liver model was bioprinted with a novel liver extracellular matrix-based bioink laden with human adipose mesenchymal stem cell-derived hepatocyte-like cells, human umbilical vein endothelial cells, and human hepatic stellate cells.

CircKDM4B Suppresses Breast Cancer Progression via the miR-675/NEDD4L Axis

[Oncogene] CircKDM4B inhibited migration and tube formation of HUVECs in vitro and angiogenesis in vivo.

Endothelial Cells Release Hybrid Extracellular Vesicles: Microvesicles That Secrete Exosomes

[Biophysical Journal] Using cultured HUVECs, scientists looked for sites of extracellular vesicle release using ultra-rapid freezing, freeze substitution, and serial section electron microscopy.

Single Cell Transcriptional Analysis of Human Endothelial Colony Forming Cells from Patients with Low VWF Levels

[Blood] Scientists observed that endothelial colony forming cells derived from patients with low Von Willebrand Factor (VWF) demonstrated alterations in baseline Weibel Palade body metrics and exhibited impaired VWF release.

Purification and Characterization of Human Adipose-Resident Microvascular Endothelial Progenitor Cells

[Scientific Reports] Scientists established a method for the isolation and purification of adipose-derived endothelial progenitor cells.

CircCHMP5 Contributes to Ox-LDL-Induced Endothelial Cell Injury through the Regulation of MiR-532-5p/ROCK2 Axis

[Cardiovascular Drugs and Therapy] Oxidized low-density lipoprotein was used to treat human umbilical vein endothelial cells to construct a cell injury model. The expression level of circCHMP5, miR-532-5p, and Rho-associated protein kinase 2 was measured using quantitative real-time PCR.

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