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HUVECs

Histone Variant macroH2A1.1 Enhances Non-homologous End Joining-Dependent DNA Double-Strand-Break Repair and Reprogramming Efficiency of Human iPSCs

[Stem Cells] Researchers evaluated the splicing isoforms of histone variant macroH2A1, macroH2A1.1 and macroH2A1.2, as potential regulators of DNA damage repair during iPSC reprogramming.

Alginate/Gelatin-Based Hydrogel with Soy Protein/ Peptide Powder for 3D Printing Tissue-Engineering Scaffolds to Promote Angiogenesis

[Macromolecular Bioscience] Researchers prepared inks that exhibited excellent shear-thinning behavior, which contributed to extrusion-based printing, and also showed good crosslinking ability by calcium chloride.

Dapagliflozin Exerts Anti-inflammatory Effects via Inhibition of LPS-Induced TLR-4 Overexpression and NF-κB Activation in Human Endothelial Cells and Differentiated Macrophages

[European Journal of Pharmacology] The authors assessed the direct anti-inflammatory effects of sodium-glucose co-transporter 2 inhibitors dapagliflozin on two cell types involved in the process of atherogenesis.

MEG8 Regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) Expression in the Endothelium

[Scientific Reports] Scientists investigated the role of maternally expressed gene 8 (MEG8) specifically in endothelial function as well as the underlying mechanism, hypothesizing that it plays an important role in cardiovascular disease via epigenetic regulation of gene expression.

Liraglutide Prevents High Glucose Induced HUVECs Dysfunction via Inhibition of PINK1/Parkin-Dependent Mitophagy

[Molecular and Cellular Endocrinology] Investigators characterized the potential effects of liraglutide, a glucagon-like peptide-1 receptor agonist, on preventing high glucose-induced endothelial dysfunction and excessive mitophagic response.

Endometrial Stromal Cell Ferroptosis Promotes Angiogenesis in Endometriosis

[Cell Death Discovery] Scientists revealed that endometrial stromal cell ferroptosis in the ovarian endometrioma may have triggered cytokine secretion and promoted angiogenesis of adjacent lesions via paracrine actions to drive the development of endometriosis.

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