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HUVECs

The Effect of Endocrine Disrupting Chemicals on the Vitronectin-Receptor (Integrin αvβ3)-Mediated Cell Adhesion of Human Umbilical Vein Endothelial Cells

[Toxicology in Vitro] Vitronectin receptor (VTNR)-expressing HUVECs were used to determine the effects of endocrine disrupting chemicals and endogenous hormones on cell adhesion to vitronectin-coated surfaces, and on VTNR activation.

Perfluorooctane Sulfonic Acid (PFOS) Inhibits Vessel Formation in a Human 3D Co-Culture Angiogenesis Model (NCFs/HUVECs)

[Environmental Pollution] Researchers found that in terms of metabolic activity, endothelial cells were much more sensitive to PFOS than fibroblasts or epithelial cells, and concluded that PFOS possesses antiangiogenic properties.

3D Spheroids of Human Placenta-Derived Mesenchymal Stem Cells Attenuate Spinal Cord Injury in Mice

[Cell Death & Disease] The authors found that 3D human placenta-derived MSCs demonstrated a significant increase in secretion of anti-inflammatory factors and trophic factors like VEGF, PDGF, FGF via QPCR and Bio-Plex assays.

Three-Dimensional Printing of Bioceramic-Induced Macrophage Exosomes: Immunomodulation and Osteogenesis/Angiogenesis

[NPG Asia Materials] 3D printed macrophage exosomes scaffolds, exhibiting a predefined structure and persistent release of exosomes, displayed distinct immunomodulatory effects and improved osteogenesis/angiogenesis.

Requirement of Direct Contact between Chondrocytes and Macrophages for the Maturation of Regenerative Cartilage

[Scientific Reports] Researchers examined the host cells that promoted cartilage maturation via cell–cell contact. Based on analysis of the transplanted chondrocytes, they examined the contribution of endothelial cells and macrophages.

USP12 Promotes Breast Cancer Angiogenesis by Maintaining Midkine Stability

[Cell Death & Disease] Investigators showed that the supernatant from ubiquitin-specific protease 12 (USP12)-overexpressing breast cancer cells could promote angiogenesis according to HUVEC migration and tube formation assays.

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