ARHGEF19 Regulates MAPK/ERK Signaling and Promotes the Progression of Small Cell Lung Cancer

Enforced ARHGEF19 expression promotes small cell lung cancer cell proliferation in vitro and its knockdown decreases cell proliferation in vitro and in vivo.
[Biochemical and Biophysical Research Communications]
Wang, Z., Kan, G., Sheng, C., Yao, C., Mao, Y., & Chen, S. (2020). ARHGEF19 regulates MAPK/ERK signaling and promotes the progression of small cell lung cancer. Biochemical and Biophysical Research Communications. https://doi.org/10.1016/j.bbrc.2020.09.085 Cite
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Costello Syndrome Model Mice with a Hras G12S Mutation Are Susceptible to Develop House Dust Mite-Induced Atopic Dermatitis

Cultured HrasG12S/+ keratinocytes exhibited increased IL-33 expression after Dermatophagoides farinae stimulation.
[Cell Death & Disease]
Katata, Y., Inoue, S., Asao, A., Kobayashi, S., Terui, H., Inoue-Shibui, A., Abe, T., Niihori, T., Aiba, S., Ishii, N., Kure, S., & Aoki, Y. (2020). Costello syndrome model mice with a Hras G12S mutation are susceptible to develop house dust mite-induced atopic dermatitis. Cell Death & Disease, 11(8), 1–15. https://doi.org/10.1038/s41419-020-02845-8 Cite
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