Tag results:
IL-6
Dermal Cell News
Melittin and Diclofenac Synergistically Promote Wound Healing in a Pathway Involving TGF-β1
[Pharmacological Research] Melittin (MEL)-diclofenac (DCL) nano-complexes exhibited better regenerated epithelium, keratinization, epidermal proliferation, and granulation tissue formation and better wound healing activity than controls. Treatment of wounded skin with MEL-DCL nano-complexes showed an increase in mRNA expression levels of collagen.
Hepatic Cell News
TM4SF5-Dependent Crosstalk between Hepatocytes and Macrophages to Reprogram the Inflammatory Environment
[Cell Reports] Scientists investigated the role of TM4SF5 in communication between hepatocytes and macrophages and its possible influence on the inflammatory microenvironment that may lead to nonalcoholic fatty liver disease.
Immune Regulation News
A Novel Cytokine Consisting of the p40 and EBI3 Subunits Suppresses Experimental Autoimmune Arthritis via Reciprocal Regulation of Th17 and Treg Cells
[Cellular & Molecular Immunology] The presence of the p40-EBI3 heterodimer was confirmed by ELISA, immunoprecipitation, and western blotting. A p40-EBI3 vector and p40-EBI3-Fc protein were synthesized to confirm the immunological role of this protein in mice with collagen-induced arthritis
Cell Therapy News
Ameliorating Effect of Umbilical Cord Mesenchymal Stem Cells in a Human Induced Pluripotent Stem Cell Model of Dravet Syndrome
[Molecular Neurobiology] Investigators evaluated the effects of human umbilical cord mesenchymal stem cell-conditioned medium in a new in vitro model of neurons differentiated from Dravet syndrome patient-derived iPSCs.
Human Immunology News
The Protein Kinase Activity of NME7 Activates Wnt/β-Catenin Signaling to Promote One-Carbon Metabolism in Hepatocellular Carcinoma
[Hepatology] High-throughput RNA-seq was used to identify the differentially expressed circRNAs upon IL-6 stimulation in intrahepatic cholangiocarcinoma cells.
Cancer Stem Cell News
miR-126 in Extracellular Vesicles Derived from Hepatoblastoma Cells Promotes the Tumorigenesis of Hepatoblastoma through Inducing the Differentiation of BMSCs into Cancer Stem Cells
[Journal of Immunology Research] Scientists explored the differentially expressed miRNAs related to tumor cell-derived extracellular vesciles (EVs) and the mechanism by which EVs regulated hepatoblastoma progression.