Researchers showed here that astrocyte elevated gene-1 (AEG-1) was overexpressed in glioma tissues and associated with a worse subtype and a poor prognosis.
[zotpress userid=” items=’EDQ7XFCH’ style=’apa’ cite=’yes’]
Scientists showed that intestine-draining mesenteric lymph nodes, not intestine proper, were the dominant site of segmented filamentous bacteria-induced intestinal Th17 cell differentiation.
[zotpress userid=” items=’GVAVI8U5′ style=’apa’ cite=’yes’]
Cough-variant asthma (CVA) is a special type of asthma, solely manifesting with coughing. Investigators suggested that airway inflammation was associated with CVA pathogenesis.
[International Archives of Allergy and Immunology]
[zotpress userid=” items=’EH5GMZ6F’ style=’apa’ cite=’yes’]
Scientists analyzed whether ultraviolet A aggravated the particulate matter-induced inflammatory cascade, which contributed to the aging of skin-derived cells.
[Photodermatology Photoimmunology & Photomedicine]
[zotpress userid=” items=’RZ9Z5AR6′ style=’apa’ cite=’yes’]
Investigators evaluated the effects of electronic cigarette (EC) refill fluids and EC exhaled aerosol residue on cultured human keratinocytes and MatTek EpiDerm™, a 3D air liquid interface human skin model.
[Toxicology in Vitro]
[zotpress userid=” items=’KFD7PZRP’ style=’apa’ cite=’yes’]
Researchers found that ethyl ferulate significantly alleviated lipopolysaccharide-induced pathological damage and neutrophil infiltration and inhibited the gene expression of proinflammatory cytokines in murine lung tissues.
[Acta Pharmacologica Sinica]
[zotpress userid=” items=’B8WZEPM2′ style=’apa’ cite=’yes’]
Investigators reported Mangiferin functionalized gold nanoparticulate agent and its immunomodulatory characteristics in treating prostate cancer.
[zotpress userid=’6445218′ items=’CP3DGJAH’ style=’apa’ cite=’yes’]
Visceral adipose-derived factors promoted vasculogenesis and the onset of metastatic dissemination by activation of STAT3, which inhibited miR-200a and enhanced ZEB2 expression, effectively reprogramming colorectal cancer cells into a highly metastatic phenotype.
[zotpress userid=” items=’LJT4S9EF’ style=’apa’ cite=’yes’]
Through transcriptomics analysis, we observed that Entamoeba histolytica infection was associated with increased expression of IL-33 mRNA in both the human and murine colon.
[zotpress userid=’7992332′ items=’J7BDLLBF’ style=’apa’ cite=’yes’]
Scientists demonstrated that melatonin had several significant effects by reducing CD11b and TLR4 expression, attenuating TLR signaling, genes involved in the inflammasome and had the potential to reduce LPS-induced inflammatory responses.
[zotpress userid=’6445218′ items=’TZQ3WXU5′ style=’apa’ cite=’yes’]
Researchers investigated whether and how cancer-associated fibroblasts (CAFs) regulated myeloid-derived suppressor cells function to enhance cancer stemness, the driving force of the cancer aggressiveness and chemotherapy refractoriness, in highly desmoplastic intrahepatic cholangiocarcinoma.
[zotpress userid=” items=’S5698YLC’ style=’apa’ cite=’yes’]