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IL-6

Influence of HEMA on LPS- and LTA-Stimulated IL-6 Release from Human Dental Pulp Cells

[Dental Materials] Researchers analyzed the formation of the pro-inflammatory cytokines TNFα and IL-6 in lipopolysaccharide (LPS)- or lipoteichoic acid (LTA)-stimulated cells from the dental pulp interface and pulp fibroblasts in the presence of the resin monomer 2-hydroxyethyl methacrylate (HEMA).

Downregulation of lncRNA NEAT1 Relieves Caerulein-Induced Cell Apoptosis and Inflammatory Injury in AR42J Cells through Sponging MiR-365a-3p in Acute Pancreatitis

[Biochemical Genetics] Investigators explored the role of long-noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) in acute pancreatitis that was induced by caerulein in rat pancreatic acinar cells AR42J.

Gymnemic Acid Protects Murine Pancreatic β-Cells by Moderating Hyperglycemic Stress-Induced Inflammation and Apoptosis in Type 1 Diabetic Rats

[Journal of Biochemical and Molecular Toxicology] Scientists delineated the role of gymnemic acid in protecting pancreatic β-cells in diabetic animals, with special reference to inflammation and apoptosis.

Angiopathic Activity of LRG1 Is Induced by the IL-6/STAT3 Pathway

[Scientific Reports] Researchers examined the role of interleukin-6 (IL-6) in defective angiogenesis mediated by leucine-rich α-2-glycoprotein 1 (LRG1). IL-6 treatment induced LRG1 expression in endothelial cells and ex vivo angiogenesis cultures and promoted vascular growth with reduced mural cell coverage.

Strategy of Stem Cell Transplantation for Bone Regeneration with Functionalized Biomaterials and Vascularized Tissues in Immunocompetent Mice

[ACS Biomaterials Science & Engineering] Scientists covalently modified alginate with RGD and QK peptides that were injected subcutaneously into immunocompetent mice.

Probiotics-Loaded Nanoparticles Attenuated Colon Inflammation, Oxidative Stress, and Apoptosis in Colitis

[Scientific Reports] Investigators explored the potential alleviating effects of dietary nano-supplement combined with bacillus strains in colitis a model.

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