IL-6

[Cell Reports] Scientists reported that high-level mitochondrial respiration and constitutive low-level glycolysis supported liver sinusoidal endothelial cells scavenger and sentinel functions

[Cell Death & Differentiation] Researchers reported that prostate leucine zipper (PrLZ) could be degraded by SPOP. PrLZ abundance was elevated in SPOP-mutant expressing prostate cancer cell lines and patient specimens.

[Aging] Investigators administrated Qi Ling (QL) to rats and collected the serum from QL-treated rats and established the co-culture system of tumor-associated macrophages/paclitaxel resistant prostate cancer cells.

[Bioengineered] The expression of HSP90 and IL-6 was upregulated and that of androgen receptor was downregulated by knocking down lung cancer metastasis-related protein 1 or GRα in CRPC cells.

[Molecular Nutrition & Food Research] Caco-2 cell monolayers were incubated with TNFα, in the absence or presence of curcumin. TNFα caused an increase in interleukin (IL)-6 and IL-8 release which was inhibited by curcumin in a dose-dependent manner

[Nature Metabolism] Scientists combined an evolutionary perspective with physiological data to propose that IL-6’s context-dependent effects on metabolism reflect its adaptive role for short-term energy allocation.