Scientists characterized tumor associated neutrophils (TANs) using flow cytometric analysis and immunofluorescence analysis. The prognostic merit of TANs in epithelial ovarian cancer was evaluated using cox regression analysis.
[British Journal of Cancer]
Human alveolar epithelial A549 cells were cultured for 24 hours in conditioned media of THP-1 monocyte-derived macrophages with 1–20 μM aesculetin.
[International Journal of Molecular Sciences]
1254621 SMTGZLHX items 1 apa default asc 1
Researchers showed for the first time that LCN2 mRNA and protein expression were strongly inducible by TNF-α in the highly metastatic human PCa cell line PC-3.
1254621 MQPKK3L9 items 1 apa default asc 1
Placental villous explants of noncomplicated placentae and BeWo cells were subjected to hypoxia. The effect of placental hypoxic-conditioned medium on intraluminal-induced contraction and endothelial barrier integrity in chorionic arteries was investigated using pressure myography.
6445212 KWIGS5EL items 1 apa default asc 1
Vangrieken, P., Remels, A. H. V., Al-Nasiry, S., Bast, A., Janssen, G. M. J., von Rango, U., Vroomans, D., Pinckers, Y. C. W., van Schooten, F. J., & Schiffers, P. M. H. (2020). Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity. Hypertension Research, 1–14. https://doi.org/10.1038/s41440-020-0528-8 Cite
Using human monocyte-derived macrophages (MDMs) from healthy donors, researchers found that cigarette smoke exposure was not associated with significant changes in the production of pro inflammatory cytokines by MDMs.
6445212 PRF9FC3I items 1 apa default asc 1
da Silva, C. O., Gicquel, T., Daniel, Y., Bártholo, T., Vène, E., Loyer, P., Pôrto, L. C., Lagente, V., & Victoni, T. (2020). Alteration of immunophenotype of human macrophages and monocytes after exposure to cigarette smoke. Scientific Reports, 10(1), 12796. https://doi.org/10.1038/s41598-020-68753-1 Cite
Researchers investigated the role of endothelial cell (EC) apoptosis in retinal hypoxia using a mouse model of ischemic retinopathy, in which vessel closure and EC apoptosis caused capillary regression and retinal ischemia followed by neovascularisation.
[Journal of Clinical investigation]