IL-8

[Environmental Toxicology] Researchers investigated the effects of glyphosate-based herbicides on antioxidant capacity, inflammatory cytokines, and autophagy of porcine intestinal epithelial cells IPEC-J2 and its molecular mechanism.

[Scientific Reports] Researchers analyzed in vitro the effect of lysophosphatidic acid (LPA)18:1 and the LPA receptor 1 (LPAR1), LPAR3, and LPAR2 inhibitor Ki16425 on cellular functions of different human breast cancer cell lines and the human breast epithelial cell line, as well as Interleukin 8, Interleukin 6 and tumor necrosis factor-alpha cytokine secretion after LPA-incubation.

[Scientific Reports] Scientists targeted Monoacylglycerol lipase (MAGL) in TNBCs, using a potent carbamate-based inhibitor AM9928 with prolonged pharmacodynamic effects. AM9928 blocked TNBC cell adhesion and transmigration across human brain microvascular endothelial cells in 3D co-cultures.

[Scientific Reports] Researchers engineered cell sheets to develop a new in vitro model of ballooned hepatocytes.

[Journal of Agricultural and Food Chemistry] The miRNA profiles in ginger and ginger exosome-like nanoparticles were analyzed using high-throughput sequencing, and the results of the sequencing were validated by real-time quantitative polymerase chain reaction.

[Journal of Reproductive Immunology] Investigators hypothesized that decidual leukocytes were altered by maternal SARS-CoV-2 infection in pregnancy and that this decidual immune response was shaped by the timing of infection during gestation.