IL-8

[Molecular Nutrition & Food Research] Caco-2 cell monolayers were incubated with TNFα, in the absence or presence of curcumin. TNFα caused an increase in interleukin (IL)-6 and IL-8 release which was inhibited by curcumin in a dose-dependent manner

[Scientific Reports] In a co-culture system of human umbilical vein endothelial cells and acute lymphoblastic leukemia (ALL) cells, serine protease inhibitor Kazal type 1 (SPINK1) exposure resulted in enhanced endothelial cell motility and ALL cells trans-endothelial migration.

[EMBO Journal] Via targeted deletion of virus-recognition innate immune pathways, scientists identified TLR7-MyD88 signaling as crucial for production of antiviral interferons, whereas TLR2 is responsible for the inflammatory IL-6 response.

[Cell Death & Disease] The authors investigated the impact of apoptotic colorectal cancer cells on neutrophils and its consequence on other immune cells of the tumor microenvironment.

[Environmental Science and Pollution Research] The authors examined the viability of BEAS-2B and mRNA/protein expression profile of oxidative stress and inflammatory response-related transcription factors Nrf2, NF-kB, and according inflammatory indicators such as IL-1, IL-6, and IL-8, with a view to evaluating the effects of different interaction models of PM2.5 on epithelial cell damage in vitro.

[British Journal of Nutrition] Researchers assessed the effect of citrus flavonoids and their intestinal metabolites on immune-mediated barrier disruption in an in vitro co-culture model.