Tag results:
JAZF1
Mesenchymal Cell News
JAZF1, YWHAE, and BCOR Gene Translocation in Primary Extrauterine Low-Grade and High-Grade Endometrial Stromal Sarcomas
[Histopathology] In extrauterine low-grade endometrial stromal sarcoma (LG-ESS), the positive rate of JAZF1 gene rearrangement was significantly lower than in uterine LG-ESS, limiting the value of JAZF1 gene translocation for diagnosis.
Pancreatic Cell News
Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion
[Diabetes] Researchers reported increased expression of miR-200c in islets from type 2 diabetes as compared with non-diabetic donors and displayed results showing reduced glucose-stimulated insulin secretion in EndoC-βH1 cells overexpressing miR-200c.
Mesenchymal Cell News
Low-Grade Endometrial Stromal Sarcoma-Like Tumors in Male with JAZF1 Gene Fusions
[Genes Chromosomes & Cancer] Researchers reported two new cases of low-grade endometrial stromal sarcoma-like sarcoma in male patients, one presenting as a periprostatic/peri-rectal mass with a JAZF1-GLI3 fusion, while the other as a paratesticular mass with a JAZF1-PHF1 fusion.
Mesenchymal Cell News
Clinicopathological and Genomic Characterization of BCORL1-Driven High-Grade Endometrial Stromal Sarcomas
[Modern Pathology] The authors described 12 BCORL1-altered uterine sarcomas with striking resemblance to BCOR-altered endometrial stromal sarcoma.