MTOR

[Cell Death & Disease] Researchers reported that nerve growth factor (NGF) facilitated lysyl oxidase-dependent cellular migration and invasion in human chondrosarcoma cells, and that NGF overexpression enhanced lung metastasis in a mouse model of chondrosarcoma.

[Experimental Cell Research] Scientists review the roles and behaviors of muscle satellite cells, characteristics of new myonuclei in muscle hypertrophy, and their relevance to sarcopenia.

[Experimental Cell Research] Researchers investigated the effects of Ad-apoptin on glycolysis, migration and invasion of non-small cell lung cancer.

[Molecules] Scientists investigated whether the autophagy inhibitor chloroquine could potentiate the anticancer effect of pterostilbene in the PDAC cell lines MIA PaCa-2 and BxPC-3, as well as in an orthotopic animal model.

[Environmental Toxicology] Dysregulated miRNAs have been promulgated as oncogenes or tumor-suppressive genes participating in the initiation and progression of colorectal cancer (CRC). Scientists reported that miR-346 was highly expressed in CRC patients.

[Oncogenesis] Scientists showed that FATP5 was downregulated in hepatocellular carcinoma tissues and even much lower in vascular tumor thrombi.